Adrenergic receptors and cardiovascular diseases

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Adrenergic Receptors Within the Cardiovascular System

THE CONCEPT that drugs react with specific receptors in living tissues to produce pharmacologic effects is believed to have originated with Langley in 19051 although Ehrlich and others had certainly conceived of specific drug-cellular interactions. Today receptors have achieved such status amnong pharmacologists to be almost commonplace in spite of the fact that their identity has not been esta...

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Adrenergic Receptors Within the Cardiovascular System

THE CONCEPT that drugs react with specific receptors in living tissues to produce pharmacologic effects is believed to have originated with Langley in 19051 although Ehrlich and others had certainly conceived of specific drug-cellular interactions. Today receptors have achieved such status amnong pharmacologists to be almost commonplace in spite of the fact that their identity has not been esta...

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Adrenergic Receptors within the Cardiovascular System.

THE CONCEPT that drugs react with specific receptors in living tissues to produce pharmacologic effects is believed to have originated with Langley in 19051 although Ehrlich and others had certainly conceived of specific drug-cellular interactions. Today receptors have achieved such status amnong pharmacologists to be almost commonplace in spite of the fact that their identity has not been esta...

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Adrenergic receptors and metabolism: role in development of cardiovascular disease

Activation of the adrenergic system has a profound effects on metabolism. Increased circulating catecholamine and activation of the different adrenergic receptors deployed in the various organs produce important metabolic responses which include: (1) increased lipolysis and elevated levels of fatty acids in plasma, (2) increased gluconeogenesis by the liver to provide substrate for the brain, a...

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Protease-activated receptors in cardiovascular diseases.

Thrombosis associated with the pathophysiological activation of platelets and vascular cells has brought thrombin and its receptors to the forefront of cardiovascular medicine. Thrombin signaling through the protease-activated receptors (PARs) has been shown to influence a wide range of physiological responses including platelet activation, intimal hyperplasia, inflammation, and maintenance of ...

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ژورنال

عنوان ژورنال: SCIENTIA SINICA Vitae

سال: 2020

ISSN: 1674-7232

DOI: 10.1360/ssv-2020-0090